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當前位置:首頁產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2375PS-RMab?ALPP/ALPPL2 Recombinant Rabbit mAb (SDT-2088-32)

S-RMab?ALPP/ALPPL2 Recombinant Rabbit mAb (SDT-2088-32)
產(chǎn)品簡介:

S-RMab?ALPP/ALPPL2 Recombinant Rabbit mAb (SDT-2088-32)

產(chǎn)品型號:S0B2375P

更新時間:2025-10-11

廠商性質(zhì):生產(chǎn)廠家

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產(chǎn)品介紹

ALPP/ALPPL2 proteins are members of the alkaline phosphatase family, which are closely related and regulated GPI-anchored proteins. ALPP, also known as placental alkaline phosphatase, and ALPPL2, also known as germ cell alkaline phosphatase or placental-like alkaline phosphatase 2, share a high degree of amino acid sequence similarity (98% homology) and have a highly restricted tissue expression pattern, primarily found in placental trophoblasts and certain tumor tissues. ALPPL2 is expressed in various cancers, including mesothelioma, ovarian cancer, and gastric cancer, and is considered a tumor-specific antigen due to its high tissue specificity. This makes it a promising target for cancer therapies, such as antibody-drug conjugates and CAR-T cell therapies.

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