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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2373NPHS1 Recombinant Rabbit mAb (SDT-2148-63)

NPHS1 Recombinant Rabbit mAb (SDT-2148-63)
產(chǎn)品簡介:

NPHS1 Recombinant Rabbit mAb (SDT-2148-63)

產(chǎn)品型號(hào):S0B2373

更新時(shí)間:2025-10-11

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NPHS1 protein, also known as nephrin, is a type-1 transmembrane protein primarily found in renal tissues, specifically at the slit diaphragm of glomerular podocytes. It is a member of the immunoglobulin family of cell adhesion molecules and plays a crucial role in the glomerular filtration barrier, functioning as an ultrafilter to exclude albumin and other plasma macromolecules from urine. Mutations in the NPHS1 gene can lead to Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

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