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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2352p27 Kip1 Recombinant Rabbit mAb (SDT-361-324)
產(chǎn)品型號：S0B2352
更新時間：2025-08-09
廠商性質(zhì)：生產(chǎn)廠家
訪問量：65
服務熱線15855403091
產(chǎn)品分類
p27 KIP1 is a member of the Cyclin Inhibitory Protein/Kinase Inhibitory Protein （CIP/KIP） family of cyclin-dependent kinase （Cdk） inhibitors. It plays roles in all phases of the cell division cycle. Its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes enforces the G1 restriction point. Thus, important cellular functions as the cell division cycle, respiration, RNA processing, translation, and cell adhesion, are under p27 KIP1 regulation. Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung.
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