Claudin 5 Recombinant Rabbit mAb (SDT-R322)

產(chǎn)品型號：S0B2283

更新時間：2025-10-10

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

Claudin-5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction （TJ） strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin-5 is an endothelial cell-specific component of TJ strands. It has been used as a marker for endothelial lesions. Claudin-5 is also found in bronchial and lung epithelial cells. In tumors, Claudn-5 expression has been found in lung adenocarcinoma and squamous carcinoma. Strong membranous expression of claudin5 and claudin7 differentiates pancreatic solid papillary neoplasm from pancreatoblastoma, acinar cell and endocrine tumors.

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