13774214275
13774214275
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產品型號：S0B2180
更新時間：2025-08-08
廠商性質：生產廠家
訪問量：62
服務熱線15855403091
The androgen receptor （AR）, ligand-induced transcription factor, is expressed in primary prostate cancer and in metastases. AR regulates multiple cellular events, proliferation, apoptosis, migration, invasion, and differentiation. Its expression in prostate cancer cells is regulated by steroid and peptide hormones [PMID: 24384911]. The elucidation of the structures of the AR DNA binding domain （DBD） and ligand binding domain （LBD） provides a new framework for understanding the functions of this receptor and leads to the development of rational drug design for the treatment of prostate cancer [PMID: 24909511].
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