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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2012Claudin 1 Recombinant Rabbit mAb (SDT-025-43)

Claudin 1 Recombinant Rabbit mAb (SDT-025-43)
產(chǎn)品簡介:

Claudin 1 Recombinant Rabbit mAb (SDT-025-43)

產(chǎn)品型號:S0B2012

更新時間:2025-10-09

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Claudin-1 is a protein that in humans is encoded by the CLDN1 gene.It belongs to the group of claudins.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

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