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產(chǎn)品中心抗體/抗原流式抗體S0B5295Rat Anti-Mouse CD192 Antibody (S-R731)
產(chǎn)品型號：S0B5295
更新時間：2025-10-09
廠商性質(zhì)：生產(chǎn)廠家
訪問量：53
服務熱線15855403091
產(chǎn)品分類
CD192, also known as CCR2, is a seven-transmembrane, G-protein-coupled receptor that belongs to the beta chemokine receptor family. It is primarily expressed on monocytes, macrophages, basophils, dendritic cells, and some T cells. CD192 acts as a receptor for several chemokines, including monocyte chemoattractant protein-1 （MCP-1/CCL2）, MCP-2/CCL8, MCP-3/CCL7, and MCP-4/CCL13. This receptor plays a crucial role in mediating monocyte chemotaxis and is involved in various inflammatory responses, such as the recruitment of monocytes into tissues during atherosclerosis, rheumatoid arthritis, and tumor formation. Additionally, CD192 has been implicated in the pathogenesis of certain cancers, where it controls the recruitment of activated macrophages that can either promote tumor cytotoxicity or inhibit tumor growth.
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