Biotin Mouse Anti-Human TCR γ/δ Antibody (S-R637)

產(chǎn)品型號：S0B5253

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：70

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

The TCR γ/δ protein is a distinctive T-cell receptor （TCR） expressed on the surface of γδ T cells, composed of a γ chain and a δ chain linked by disulfide bonds to form a heterodimer, belonging to the immunoglobulin superfamily. Unlike the conventional αβ TCR, the γδ TCR can directly recognize a broad range of antigens （e.g., phosphorylated metabolites, lipids, stress proteins） without requiring MHC presentation, granting it broader antigen specificity. Its variable （V） region diversity arises from V, （D）, and J gene segment rearrangements, though it exhibits less diversity than the αβ TCR. γδ T cells are primarily found in mucosal tissues, skin, and the gut, playing crucial roles in early immune defense, tumor surveillance, and tissue repair. They can rapidly secrete cytokines （e.g., IFN-γ, IL-17） or exert cytotoxic effects, serving as key effector cells bridging innate and adaptive immunity.

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