FITC Rat Anti-Mouse CD104 Antibody (S-R716)

產(chǎn)品型號：S0B5244

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

Integrin beta 4 （CD104） is a key subunit of the integrin family, primarily functioning as a receptor for laminins and often associating with the alpha 6 subunit to form the α6β4 integrin complex. This transmembrane glycoprotein receptor plays a crucial role in mediating cell-matrix adhesion and signaling, which regulates gene expression, cell growth, and migration. ITGB4 is particularly important in maintaining the stability of hemidesmosomes, which anchor epithelial cells to the basement membrane. Additionally, its expression and activity are implicated in various biological processes, including wound healing, tissue integrity, and cancer progression. Abnormal mutations or dysregulation of ITGB4 have been associated with diseases such as epidermolysis bullosa with pyloric atresia.

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