Rat Anti-Mouse CD39 Antibody (S-R641)

產(chǎn)品型號(hào)：S0B5042

更新時(shí)間：2025-10-08

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD39 （Ectonucleoside triphosphate diphosphohydrolase-1, encoded by the ENTPD1 gene） is an ectoenzyme that hydrolyzes extracellular ATP into AMP, serving as the rate-limiting enzyme in the generation of adenosine. In the tumor microenvironment, CD39 works in concert with CD73 to ultimately produce immunosuppressive adenosine, which inhibits antitumor immune responses. CD39 is widely expressed on the surface of various immune cells, including T cells, B cells, natural killer cells, dendritic cells, and macrophages. Due to its critical role in immune suppression, CD39 has emerged as a promising target for cancer immunotherapy, with several inhibitors and antibody drugs currently under clinical investigation.

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