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S0B5043Rat Anti-Mouse CD163 Antibody (S-R608)

產(chǎn)品型號(hào):S0B5043
更新時(shí)間:2025-10-08
廠商性質(zhì):生產(chǎn)廠家
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CD163 is a type I membrane protein primarily expressed on the surface of monocytes and macrophages and belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. It plays a crucial role in regulating immune responses and clearing heme proteins. CD163 binds to haptoglobin-hemoglobin complexes, facilitating iron recycling and protecting tissues from oxidative damage. As a marker of M2-type macrophages, CD163 is associated with anti-inflammatory functions by inhibiting the production of pro-inflammatory cytokines. In pathological conditions, the expression levels of CD163 are linked to various diseases, including inflammatory disorders, cancer, and viral infections. Soluble CD163 (sCD163) is often used as a biomarker for disease monitoring and assessment.
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