Mouse IgM OneStep ELISA Kit

產(chǎn)品型號：S0C3022

更新時間：2025-10-11

廠商性質(zhì)：生產(chǎn)廠家

訪問量：210

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

Mouse immunoglobulin M （IgM） is a crucial component of the humoral immune system and is the first antibody produced by B-cells in response to an antigenic challenge. It exists in two forms: a pentameric （19S） form found in serum and a monomeric （8S） form on the surface of lymphocytes. The IgM pentamer, which is the predominant form in circulation, consists of five monomeric units and has a molecular weight of approximately 900 kDa, while the hexameric form has a molecular weight of about 1050 kDa. Each monomer of IgM is composed of two heavy chains and two light chains, with the heavy chain having four constant domains （CH1-CH4） and the light chain having one constant domain （CL）. The CH4 domain facilitates oligomerization, leading to the formation of penta- or hexamers, and these oligomers are covalently linked via disulfide bonds, resembling a snowflake structure. A joining （J） chain, a 15 kDa polypeptide, is essential for the secretion of IgM into mucosal areas.

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