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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原偶聯(lián)抗體S0B1569p53 Recombinant Rabbit mAb (Alexa Fluor??555 Conjugate) (SDT-R118)

p53 Recombinant Rabbit mAb (Alexa Fluor??555 Conjugate) (SDT-R118)
產(chǎn)品簡介:

p53 Recombinant Rabbit mAb (Alexa Fluor??555 Conjugate) (SDT-R118)

產(chǎn)品型號(hào):S0B1569

更新時(shí)間:2025-10-10

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P53 is a gene that encodes for the p53 tumor suppressor protein, commonly referred to as the “Guardian of the Genome" [PMID: 1614522]. The p53 protein is a transcription factor that controls the output of many biological processes according to the type of cellular stress signal input. Stress signals known to activate p53 include oncogene activation, DNA damage, and replication stress [PMID: 28886379]. In response to these stresses, p53 undergoes post-translational modifications, promotes the transcription of genes involved in specific cell responses according to the stress type thereby controlling the cell’s fate [PMID: 15510160]. When the p53 protein is mutated or aggregated, it loses its function, resulting in tumor progression and growth [PMID: 29789497].

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