BSEP Recombinant Rabbit mAb (SDT-045-13)

產(chǎn)品型號(hào)：S0B2151

更新時(shí)間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

The bile salt export pump BSEP is critically involved in secretion of bile salts into bile. Its function can be disturbed or abolished by inherited mutations. This will lead to progressive intrahepatic cholestais and severe liver disease. In addition to mutations, Bsep can be inhibited by acquired factors such as for example xenobiotics or drugs, aberrant bile salt metabolites or pregnancy. This inhibition will lead to acquired cholestasis. Some drugs are now known to be competitive inhibitors of Bsep. In addition, a polymorphism in the gene coding for Bsep has been identified as a potential susceptibility factor for acquired cholestasis [PMID: 20028269].

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