PercP-Cy5.5 Mouse Anti-Rat CD4 Antibody (S-R631)

產(chǎn)品型號(hào)：S0B5460

更新時(shí)間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

訪問(wèn)量：81

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

uPAR/CD87：腫瘤微環(huán)境中的“多面手”

從實(shí)驗(yàn)室到臨床：蛋白激酶藥物的輝煌20年

功能性抗體：如何解鎖其在生物醫(yī)學(xué)研究中的無(wú)限潛能？

致癌分子的失控狂飆：EGFR 信號(hào)通路如何驅(qū)動(dòng)腫瘤生長(zhǎng)？

產(chǎn)品介紹

CD4 is a glycoprotein expressed on the surface of certain immune cells, most notably helper T cells. It is a member of the immunoglobulin superfamily and has four immunoglobulin-like domains （D1 to D4）. CD4 acts as a co-receptor with the T-cell receptor （TCR） to recognize antigens displayed by MHC class II molecules on antigen-presenting cells. The D1 domain of CD4 binds to the β2 region of MHC class II, bringing the TCR complex and CD4 into close proximity. This allows the tyrosine kinase Lck, bound to the cytoplasmic tail of CD4, to phosphorylate tyrosine residues on the cytoplasmic domains of CD3, amplifying the signal generated by the TCR. CD4 is also the primary receptor for the human immunodeficiency virus （HIV）, and its interaction with the HIV gp120 protein is a key step in viral entry.

上一個(gè)：S0B5461PercP-Cy5.5 Rat anti-Mouse CD4 antibody (S-R542)