Alexa Fluor? 647 Mouse Anti-Human CD24 Antibody (S-R576)

產(chǎn)品型號(hào)：S0B5334

更新時(shí)間：2025-10-09

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產(chǎn)品介紹

CD24 is a highly glycosylated cell surface protein that is anchored to the cell membrane via a glycosyl-phosphatidylinositol （GPI） anchor. It is widely expressed in various cell types, including hematopoietic cells such as B cells, T cells, granulocytes, dendritic cells, and macrophages, as well as non-hematopoietic cells like keratinocytes and neurons. CD24 plays a crucial role in immune cell maturation and regulation of immune responses. In cancer, CD24 is overexpressed on tumor cells and interacts with the inhibitory receptor Siglec-10 on immune cells, helping tumor cells evade immune detection and attack. This interaction has led to its exploration as a potential target for cancer immunotherapy, with promising results from clinical trials of monoclonal antibodies and other targeted therapies.

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