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S0B5019Armenian hamster Anti-Mouse/Human Helios Antibody (S-R640)

產(chǎn)品型號(hào):S0B5019
更新時(shí)間:2025-10-08
廠商性質(zhì):生產(chǎn)廠家
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Helios protein (encoded by the IKZF2 gene) is a member of the Ikaros family of transcription factors and contains multiple zinc finger domains that facilitate DNA binding and the formation of homodimers or heterodimers. It is predominantly expressed in T cells, regulatory T cells (Tregs), certain B cell subsets, and hematopoietic and epithelial tissues. Helios plays a crucial role in T cell activation, proliferation, and the stability and function of Tregs. Additionally, Helios has been identified as a potential biomarker in autoimmune diseases and may influence tumor development by regulating gene expression and modulating cell differentiation and proliferation.
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