APC Mouse Anti-Human CD123 Antibody (S-R442)

產(chǎn)品型號(hào)：S0B1734

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問(wèn)量：62

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類(lèi)

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

uPAR/CD87：腫瘤微環(huán)境中的“多面手”

從實(shí)驗(yàn)室到臨床：蛋白激酶藥物的輝煌20年

功能性抗體：如何解鎖其在生物醫(yī)學(xué)研究中的無(wú)限潛能？

致癌分子的失控狂飆：EGFR 信號(hào)通路如何驅(qū)動(dòng)腫瘤生長(zhǎng)？

產(chǎn)品介紹

The CD123 protein, also known as the Interleukin-3 receptor subunit alpha （IL-3RA） or CD123, is a crucial component of the interleukin-3 （IL-3） receptor complex and belongs to the Type I cytokine receptor family, specifically the Class 5 subfamily. CD123 serves as the high-affinity receptor for IL-3, forming a heterodimeric receptor complex with the β chain （CSF2RB）. This protein mediates the stimulatory effects of IL-3 on the proliferation and differentiation of various hematopoietic cells, including pluripotent hematopoietic stem cells and lineage-committed cells. CD123 is expressed on normal plasmacytoid dendritic cells, basophils, monocytes, and eosinophils, and is overexpressed in various hematologic malignancies. In clinical research, the expression of CD123 is associated with chemotherapy resistance and high-risk genetic alterations in certain leukemias, such as acute myeloid leukemia （AML）.

上一個(gè)：S0B1731FITC Mouse Anti-Human CD11c Antibody (S-R424)