FITC Rat Anti-Mouse CD83 Antibody (S-R522)

產(chǎn)品型號：S0B1732

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：93

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

uPAR/CD87：腫瘤微環(huán)境中的“多面手”

從實驗室到臨床：蛋白激酶藥物的輝煌20年

功能性抗體：如何解鎖其在生物醫(yī)學(xué)研究中的無限潛能？

致癌分子的失控狂飆：EGFR 信號通路如何驅(qū)動腫瘤生長？

產(chǎn)品介紹

CD83 is a member of the immunoglobulin superfamily, expressed in both membrane-bound and soluble forms. It is most highly and stably expressed by mature dendritic cells （DCs）, playing a critical role in their maturation, activation, and homeostasis. CD83 is not a typical co-stimulatory molecule but rather a key factor in controlling and resolving immune responses. It is essential during the differentiation of T and B lymphocytes and the development and maintenance of tolerance. The membrane-bound form of CD83 （mCD83） is found on various activated immune cells, while soluble CD83 （sCD83） is elevated in the serum of patients with autoimmune diseases and some hematological malignancies, exhibiting immune suppressive functions. CD83's interaction partners and signaling pathways remain not fully understood, but it is emerging as a promising immune modulator with therapeutic potential in conditions such as autoimmune disease, graft-vs.-host disease, transplantation, and hematological malignancies.

上一個：S0B1728PerCP-Cy5.5 Mouse Anti-Human CD11a Antibody (S-R402)