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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原流式抗體S0B1730PerCP-Cy5.5 Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)

PerCP-Cy5.5 Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)
產(chǎn)品簡(jiǎn)介:

PerCP-Cy5.5 Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)

產(chǎn)品型號(hào):S0B1730

更新時(shí)間:2025-10-08

廠商性質(zhì):生產(chǎn)廠家

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CD161 is a C-type lectin-like membrane receptor expressed at high levels on NK, NKT, Th17, Mucosa Associated Invariant T cells (MAITs), non-MAIT CD8+, tissue-resident memory cells (TRMs), αβ CD4+ T cells and CD8+ T cells. CD161 levels increase when αβ T cells enter tissues. The ligand for CD161 is the lectin-like transcript 1 (LLT1). CD161/LLT1 engagement inhibits NK cell function but can inhibit or enhance αβ T cell function depending on the co-stimulatory molecules involved. The inhibitory capacity of αβ T cells can be neutralized by blocking CD161. CD161 expression on γδ T cells is associated with enhanced IFN-γ and IL-17 production and enhanced endothelial transmigration.

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