Rat Anti-Mouse CD83 Antibody (S-R522)

產(chǎn)品型號：S0B1134

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：58

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD83 is a member of the immunoglobulin superfamily, expressed in both membrane-bound and soluble forms. It is most highly and stably expressed by mature dendritic cells （DCs）, playing a critical role in their maturation, activation, and homeostasis. CD83 is not a typical co-stimulatory molecule but rather a key factor in controlling and resolving immune responses. It is essential during the differentiation of T and B lymphocytes and the development and maintenance of tolerance. The membrane-bound form of CD83 （mCD83） is found on various activated immune cells, while soluble CD83 （sCD83） is elevated in the serum of patients with autoimmune diseases and some hematological malignancies, exhibiting immune suppressive functions. CD83's interaction partners and signaling pathways remain not fully understood, but it is emerging as a promising immune modulator with therapeutic potential in conditions such as autoimmune disease, graft-vs.-host disease, transplantation, and hematological malignancies.

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