Mouse Anti-Human CD19 Antibody (S-R503-1)

產(chǎn)品型號(hào)：S0B0960

更新時(shí)間：2025-10-07

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

CD19 is a transmembrane glycoprotein and a member of the immunoglobulin superfamily, predominantly expressed on B lymphocytes, making it a significant marker for B cell development and function. It plays a crucial role in B cell activation, signal transduction, and growth regulation. CD19 is involved in the B cell receptor （BCR） signaling pathway, enhancing B cell activation thresholds and proliferation. In the context of disease, CD19 is highly expressed in most B cell malignancies, including acute lymphoblastic leukemia （ALL）, chronic lymphocytic leukemia （CLL）, and B cell lymphomas, making it a promising target for immunotherapy. The CD19 molecule is also implicated in autoimmune and immunodeficiency disorders, with mutations in CD19 associated with severe immunodeficiency syndromes characterized by reduced antibody production.

上一個(gè)：S0B0961Mouse Anti-Human CD19 Antibody (S-R503-2)