Hemoglobin A1c (HbA1c) Recombinant Rabbit mAb (SDT-192-53-1)

產(chǎn)品型號(hào)：S0B3222

更新時(shí)間：2025-10-07

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

HbA1c is a glycated protein in which glucose binds with N-terminal valine residue in the β chain of hemoglobin nonenzymatically. Glycated protein is produced by the two-step nonenzymatic reaction called the Maillard early-phase reaction. First, the free amino group of protein and the aldehyde group of glucose form the Schiff base, which produces a substance called aldimine. This reaction is relatively quick and reversible. Then, this aldimine becomes ketoamine by the Amadori rearrangement reaction, leading to the production of stable Amadori product, that is, glycated protein. This reaction progresses slowly and is almost irreversible. Since the speed of production of glycated protein is proportional to the plasma glucose level, the glycation rate of protein is proportional to the plasma glucose level at the time of production. As HbA1c is produced slowly corresponding to the plasma glucose levels and survives for about 120 days, the life-span of red blood cells, it is an excellent index for long-term glycemic control.

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